Scientists（Institute）
Wang Jian
发布时间：2011-09-15
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Wang Jian, Ph.D./Professor.(Head, Department of Reproductive Medicine & Biotechnology, SIPPR; Deputy Director, SIPPR; Deputy Director, NPFPC Key Laboratory of Contraceptive Drugs and Devices; Supervisor of PhD candidate, major in Pharmacology, Fudan University, Shanghai.)
After receiving his bachelor degree in biochemistry from East China University of Science & Technology in 1991, Shanghai, China, Dr Wang joined the Department of Reproductive Medicine & Biotechnology, SIPPR, and has embarked on research of reproductive regulation. Supported by a research training grant of WHO, Dr Wang had been worked in the Lab of Uterine Biology as a Visiting Research Officer under the supervision of Professor Lois Salamonsen and Dr Guiying Nie during 1996 ~ 1997. Then, he respectively got the master degree in immunology in 2001 and PhD degree in genetics in 2006 from Fudan University, Shagnhai, China. Dr Wang has focused his research interests in investigating the molecular mechanisms underlying the embryo implantation and female infertility related diseases, as well as the development of novel contraceptives. He has published over 50 peer-reviewed publications, and applied for 19 patents. Dr Wang has also serviced to the scientific communities as: Vice President, Association of Reproductive Biology, China Zoological Society; Vice President, Youth Committee, Association of Family Planning, Chinese Medical Society;Member, China Healthy Birth Science Association; Member, Academic Committee, Shanghai Key Laboratory of Molecular Andrology; Member, Academic Committee, Shandong Provincial Key Laboratory of Improving Birth Outcome Technique.
Selected Publications during 2007-2010：1. J Wang, et al., (2007), Immunoneutralization of Endometrial Monoclonal Nonspecific Suppressor Factor Beta (MNSFb) Inhibits Mouse Embryo Implantation In Vivo. Molecular Reproduction and Development, 74: 1419-1427.
2. ZG Sun, HJ Shi, Z Gu, J Wang*, Shen QX., (2007), A single intrauterine injection of the serine protease inhibitor 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride reversibly inhibits embryo implantation in mice. Contraception, 76: 250-255.
3. Xuan Zhou, Jian Wang, et a.l., (2007), Identification of the Gene imds-60 in Mouse Epididymis. Acta Biochimica et Biophysica Sinica, 39(12): 939–946.
4. Wang WQ, Li YH, Wang J, et al., (2009), NDRG3 is an androgen regulated and prostate enriched gene that promotes in vitro and in vivo prostate cancer cell growth. International Journal of Cancer, 124: 521-530.
5. Zhaogui Sun,…, Jian Wang*, (2009), Expression of the novel gene Embryo Implantation Factor 2 (EMO2) in the mouse uterus at the implantation sites. Fertility and Sterility, 91 (5 Suppl): 2116-2122..
6. Ren-wei Su,…, Jian Wang*, (2009), The uterine expression of SEC63 gene is up-regulated at implantation sites in association with the decidualization during the early pregnancy in mice. Reproductive Biology and Endocrology , 7(1):12.
7. Wang J, Wang J, et al., (2009), Proteomic analysis of seminal plasma from asthenozoospermia patients reveals proteins that affect oxidative stress responses and semen quality. Asian Journal Andrology, 11(4):484-491.
8. Wei-li Shi, Ting-yan Shi, Zhe-yu Chen, Ju-fang Lin, Xiao-feng Jia, Jian Wang* and Hui-juan Shi (2010). Generation of sp3111 transgenic RNAi mice via permanent integration of small hairpin RNAs in repopulating spermatogonial cells in vivo. Acta Biochimica et Biophysica Sinica , 42(2):116-121.
9. WX Xu, YP He, J Wang, et al., (2010). Mapping of all precise linear B cell epitopes on E7 protein from HPV type 58. American Journal of Reproductive Immunology, 64(Suppl 1): 12-13.
10. Peter K Nicholls, Zhaogui Sun, Sophea Heng, Ying Li, Jian Wang and Guiying Nie, (2011). Embryo implantation is closely associated with dynamic expression of proprotein convertase 5/6 in the rabbit uterus. Reproductive Biology and Endocrinology 2011, 9:43.
11. YH Jiang, …, Jian Wang* , (2011). The serine protease inhibitor 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride (AEBSF) inhibits the rat embryo implantation in vivo and interferes the cell adhesion in vitro. Contraception, (in press).
（*: As correspronding author）
Tel: 021-64034148; Email: wangjiansippr@126.com
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