Niu Zhenmin, male, born in October 1978, Ph.D./Associate Professor, PI. In 2001, he acquired his bachelor’s degree of Science in Biology from Fudan University. In 2018, he graduated from Fudan University as a Pd.D. in Genetics. 
In August 2001, he joined Chinese National Human Genome Center at Shanghai (CHGC), mainly engaged in medical genetics research. He cloned a possible pathogenic gene SSH1 and its mutation site in a large family of porokeratosis the first time in the world. And he found that there is a large loss of heterozygosity (LOH) covering the pathogenic gene in lesions. Research papers were published in the authoritative dermatology journal J Invest Dermatol, Hum Mutation and Hum Genetics. For the first time, he put forward the viewpoint that cholelithiasis has mitochondrial genetic characteristics and found that the mitochondrial haplogroup B4bd of an ancient East Asian population is significantly related to the incidence of cholelithiasis and proposed that mitochondrial 829G variation is a high-risk genetic locus of cholelithiasis in Chinese. The research was published in the authoritative journal Cellular and Molecular Gastroenterology and Hepatology and was selected as the cover paper. This research has won four awards, including Shanghai Science and Technology Progress Award and Medical Science and Technology Award of Chinese Medical Association. At first, he discovered that ankylosing spondylitis is related to non-MHC proteasome genes. He carried out research on the pathogenesis of proteasome, which expanded the related contents from heredity to phenotype of ankylosing spondylitis. These research papers were published by Ann Rheum Dis and Viruses, authoritative journals of rheumatic arthritis, and several related patents were authorized. Up to now, he has published more than 40 scientific research papers and obtained more than 10 authorized invention patents.
Main research directions: 
1. Explore the genetic pathogenic factors of rheumatic arthritis and autoimmune diseases, including ankylosing spondylitis, psoriasis and osteoarthritis, and carry out functional research on risk genes; Systematically describe the transcriptomics characteristics of rheumatic arthritis, and search for biomarkers for auxiliary prevention, diagnosis and treatment. 
2. Research on pathogenic genes of various familial hereditary diseases; Genetic analysis of single gene diseases and complex diseases; Detection of pathogenic genes of cleft lip and palate; Human genetics and genomics.